What Is The Best Medication For Nerve Pain?

What is the best medication for nerve pain?

When you have nerves, managing your pain is usually most effective with a multimodal therapy strategy that combines various forms of care rather than depending just on one. Never pain also known as neuropathic pain or Neuropathy which refers to the discomfort felt close to the nerves. But with so many medications available, the question generally arises about what is the best medication for nerve pain.

There are various treatments available such as anticonvulsants, mild opioids, certain antidepressants, anti-inflammatories, and other treatments that act as Pain relievers. We will be suggesting some of the best medications for nerve pain with all the essential details.

What causes Nerve pain?

It takes place when the tissue in the body is damaged. and is called Neuropathy. Damage to one of your nerves is what causes nerve pain. It can have a variety of different sensations, including burning, numbness, tingling, and intense shooting pain. Additionally, it may develop into a chronic condition if it is not successfully treated.
Also, excessive alcohol use might cause neuropathy. This might be a result of alcohol-induced dietary deficits and toxic nerve damage. Some drugs may also occasionally result in neuropathic pain. Neuropathic pain, however, may occasionally have no apparent explanation.

Many medical diseases can harm the nerves, resulting in neuropathic pain. These consist of:

  • Leprosy (HIV) Hansen’s Illness
  • Stroke and Heart Attack
  • Vascular Anomalies
  • Cardiovascular Disease
  • Guillain-Barre Disease
  • Autoimmune Diseases
  • Cancer, Diabetes, and cancer therapies like Chemotherapy
  • Neurological disorders like Parkinson’s Disease and Neurodegenerative Disorders like Multiple Sclerosis.

How does a painful nerve feel?

A certain type of pain called “nerve pain” (neuralgia) frequently has a shooting, stabbing, or burning sensation. It could prove difficult to cure nerve pain. Nerve pain can have different effects for different people.
Other times, irritants like strong winds, cold weather, or low heat might cause nerve discomfort even when they shouldn’t. Musculoskeletal discomfort, on the other hand, is frequently worse by exercise or movement.

Can medicines treat Nerve Pain and reduce pain?

Both the efficacy and the level of existence can be increased with the use of Nerve Pain medications. However, neuropathic pain is usually a complex issue that can be challenging to identify and would need a multimodal treatment, including prescription medicine, physical therapy, therapy, and in some cases, surgery.

What is the Best Medication for Nerve Pain?


Anticonvulsants like Gabapentin and Pregabalin are very helpful for nerve pain. Pregabalin and Gabapentin are particularly good for treating Postherpetic Neuralgia, Diabetic Neuropathy, and Spinal Cord Injury Pain. They belong to the family of anti-seizure or anti-epileptic drugs.

Anti-seizure medicine is also used to treat nerve pain. But if you are using it then you may have to be monitored regularly by your doctor. The type of Anticonvulsant suggested by the doctor depends on which type of pain you have.

Some other Anti-Seizure Drugs suggested by the doctors are:

  • Valproic acid (Depakene)
  • Carbamazepine
  • Lamotrigine (Lamictal)
  • Phenytoin (Dilantin)
  • Oxcarbazepine (Trileptal, Oxtellar XR)

The general side effects of the Anti-Seizure Drugs are:

  • Double vision
  • Nausea
  • Headache
  • Liver damage
  • Loss of coordination
  • Vomiting
  • Drowsiness


Certain antidepressant classes may be the primary choice for treating Neuropathic Pain in addition to Anticonvulsants. Specialists in nerve pain frequently suggest two main categories.
For many years, Tricyclic Antidepressants have been prescribed. Although they aren’t used as frequently today to treat depression, they can be quite helpful in limiting the symptoms of nerve pain. These medications have potential side effects, including nausea, upset stomach, dizziness, and constipation. For those who have particular ailments, such as cardiac issues, they might not be safe.

SNRIs(Serotonin and Norepinephrine Reuptake Inhibitors) are a more recent class of antidepressants that seem to relieve nerve discomfort. These medications typically cause fewer negative effects than Tricyclic Antidepressants. Some people, particularly older people with heart problems might find them to be safer. They might not, however, be as successful as Tricyclics in relieving nerve pain.


Mild pain in the nerves may be treated with analgesics that are available without a prescription such as Acetaminophen and NSAIDs like Ibuprofen and Naproxen.
Other painkillers, however, work better in treating pain signals that come from injured nerve tissues.

Opioid painkiller:

To stop the transmission of pain signals, the afflicted nerves can be administered with nerve blocks (injections of steroids, local anesthetics, and other drugs). These treatments, which are typically referred to as Brain Stimulation, Spinal Cord Stimulation, and Peripheral Stimulation, entail electrically stimulating a person’s spinal cord in order to treat those who do not get relief from nerve pain medicines and nerve blocks.

Some medicine for opioid medicine involves:

Other Treatments For Nerve Pain:

There are more methods to manage Neuropathic Pain, such as:

Transcutaneous Electrical Nerve Stimulation (TENS): This involves applying a low-voltage electrical current to the area of your discomfort or close by, which may change how you perceive it.

Physical Therapy: Using a number of methods, including stretches and range-of-motion exercises, doctors try to strengthen muscles and lessen discomfort.

Surgery: To decompress nerves in the extremities, this typically requires one or two surgical incisions.

Intravenous immune Globulin and Plasma Exchange:– In Plasma Exchange, your blood’s plasma is taken out, replaced with brand-new plasma, and then given back to you. Antibodies are delivered via an IV in Intravenous Immune Globulin.

How can you avoid experiencing nerve pain?

In addition to drugs for nerve pain, the following actions could ease neuropathic pain:

  • Both physical treatment and massage
  • Hot baths
  • Posture modification Ergonomic workspace
  • Yoga, stretches, and meditation
  • Lots of relaxation and sleep

Read More:

What Pain Medication can I take with Gabapentin?

Codeine vs Hydrocodone: Your Updated Guide

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