Artvigil vs Modafinil(How To Fight Excess Sleepiness)

Artvigil vs Modafinil

Excessive Daytime Sleepiness (EDS) is a major public health concern for many patients with sleep disorders. EDS is also sometimes interchangeably used for Hypersomnia and hypersomnolence. According to some foundations, it is found that EDS is considered a very common symptom that affects 10% to 20% of the general population.

These EDS sometimes lead to ADHD. Sleepiness is caused by insufficient or poor sleep quality. Multiple neurological, psychological, cardiac, and pulmonary disorders, among others, may all play a role. Obesity, depression, aging, and inadequate sleep are all risk factors for excessive sleepiness.

Individuals are concerned about the treatment options for this complication. Stimulant medication may be prescribed in some cases to allow for more normal daytime functioning. Here we’re going to describe a parallel comparison of Artvigil vs Modafinil which are usually recommended for sleep problems. So, let’s move ahead and learn everything about these two drugs in a simplified way.

What is Artvigil and its Uses?

In the category of “smart drugs” Artvigil makes its identity as a strong cognitive enhancer among other nootropic drugs. Artvigil is the brand name for the Armodafinil drug. This nootropic drug promotes wakefulness and is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder.

Artvigil is believed to be an excellent substitute for Modafinil and the cheapest generic Armodafinil brand which is currently available in the market.

Uses of Artvigil:

As with all nootropics, Artvigil is used to improve concentration, cognition, and wakefulness. It is a powerful smart drug that will help anyone boost their productivity on a daily basis. This smart drug is popular among high achievers who need to focus more intensely on their work.

This cognitive enhancer is generally prescribed for individuals who are suffering from narcolepsy, obstructive sleep, sleep apnea or shift work sleep disorder. Artvigil is also beneficial for people who are tired all the time, have stressful jobs, have college work that needs to be finished or have important tasks that need to be completed.

Artvigil is also used off-label for some other complications which include Attention Deficit/Hyperactivity Disorder (ADHD), chronic fatigue syndrome, and major depressive disorder.

What is Modafinil and its Uses?

The generic form of Modafinil is known as Provigil. Modafinil is a prescription-only nootropic drug that is commonly used to treat excessive sleepiness caused by narcolepsy, sleep apnea, and other sleep disorders.

Modafinil comes under the section of stimulants. This medication has been approved by the Food and Drug Administration (FDA) in the United States (US) for the treatment of adults suffering from sleep disorders such as narcolepsy, obstructive sleep apnea, and various other sleep disorders.

Modafinil is commercialized as a wakefulness-promoting agent in the market. This nootropic drug is only available with a prescription. This stimulant drug helps to improve wakefulness, and strength to stay focused for a long period with lesser side effects. It is also believed that Modafinil is the first choice for many nootropic drug users. This stimulant is a Schedule IV prescription drug.

Uses of Modafinil:

Modafinil is a drug approved by the Food and Drug Administration that is used for diagnosing and treating narcolepsy, sleep apnea, hypersomnia, insomnia, excessive sleeping disorder (ESD), and other sleeping disorders.

This medication is used to treat daytime sleepiness caused by narcolepsy, obstructive sleep apnea, and shift work sleep disorder. It reduces extreme sleepiness by modulating the levels of chemical messengers in the brain and exerting a stimulant effect.

This nootropic drug is a prescription-only medication and is recommended only to treat various sleep disorders and narcolepsy. However, it has the potential to be misused, as it is also used off-label for the treatment of ADHD, depression, weight loss, anxiety, etc.

Best Recommended doses of Artvigil and Modafinil:

Dosage of Artvigil:

Artvigil is a prescription-only medicine. The active ingredient of this nootropic drug is Armodafinil. It consists of varied dosage strengths which include 75 mg, 150 mg, and 300 mg. According to studies, more than half of the people who are regular users of nootropic drugs showed satisfactory results after having been administered 150 mg of Artvigil drug.

Mentioned below is a small breakdown of some common and most often recommended dosage of Artvigil:

  • A dose of 75 mg provides 6-9 hours of cognitive performance and basically, it is for novice patients.
  • The Most recommended dose which offers at least 12 hours of cognitive benefits and side effects tends to be very minor or non-existent at this dosage.
  • This dose is very rare and is not recommended for novice patients. 300 mg is typically for individuals who are in search of more than 20 hours of pure cognitive enhancement. The possibility of side effects occurring in a person when taking this dosage may be very high, especially with regard to stomach problems and insomnia.

Note: The information given above is used for general purposes only. Precise details may vary.

Dosage of Modafinil:

Modafinil is an FDA-approved medication that is classified as a Controlled Substance Class IV. It is considered a prescription-only medicine. Modafinil is available in the form of oral tablets and with dosage strengths of 100 mg and 200 mg. This stimulant drug is meant to be used for long-term treatment. However, be sure to take the dosage as prescribed by your healthcare professional.

Comparison of Artvigil and Modafinil:

Artvigil and Modafinil are both prescription-only medications that are used to treat excessive daytime sleepiness (EDS) associated with narcolepsy, shift work sleep disorder, and obstructive sleep apnea/hypopnea syndrome. Similar to other medications, these are also sometimes used off-label for the improvement of cognitive functioning or attention-deficit/hyperactivity disorder (ADHD).

Now, we are giving you a slight knowledge about the similarities and differences between these two drugs.


  • Artvigil and Modafinil are considered wakefulness-promoting drugs that are often used for the treatment of Excessive Sleeping Disorder (ESD), narcolepsy, and other sleeping disorders.
  • Both medications are generally well-tolerated and have a relatively low risk of serious side effects.
  • The primary purpose of both drugs consists of improvement in alertness, wakefulness, and improvement in cognitive performance particularly for individuals who are suffering from EDS and other sleep problems.


  • The generic form of Modafinil is Artvigil. Artvigil is cheaper than Modafinil and it is considered one of the less expensive nootropic stimulants among all the “smart drugs”.
  • The efficacy of Artvigil lasts longer than Modafinil.
  • Modafinil has a shorter half-life than Artvigil.
  • Artvigil may be determined more effective than Modafinil for some people with EDS.
  • Artvigil may also increase the likelihood of certain side effects such as insomnia and headaches.

Side Effects: Artvigil and Modafinil


Take a look at some most common side effects of Artvigil:

  • Headache
  • Sweating
  • Nervousness
  • Shortness of breath
  • Diarrhea
  • Nausea
  • Dry mouth
  • Anxiety
  • Dermatitis
  • Rash
  • Palpitations
  • Depression
  • Upset stomach
  • Agitation
  • Heartburn
  • Tingling in the arms
  • Fever
  • Difficulty in sleeping
  • Numbness
  • Loss of appetite
  • Lack of attention


A list of the most often side effects after taking Modafinil drug is mentioned below:

  • Diarrhea
  • Chest pain
  • Runny nose
  • Dizziness
  • Dry mouth
  • Indigestion
  • Nausea
  • Anxiety
  • Nervousness
  • Weight loss
  • Back pain
  • Difficulty in sleeping

Uncommon side effects of Modafinil:

  • Fast heartbeat
  • Vertigo
  • Constipation
  • Confusion
  • Tremor
  • Depression


Overall, Artvigil and Modafinil are very similar drugs in general. They both improve wakefulness and alertness and have a low potential for abuse. If you are thinking about taking Artvigil or Modafinil, you should consult with your healthcare expert first.

Your doctor/physician can advise you on the best drug for you and keep an eye out for any potential side effects. Both Artvigil and Modafinil can cause side effects. Hence it is often given under the supervision of a doctor.

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