What is tramadol
Tramadol is a prescription medicine used as an analgesic drug to treat moderate to severe chronic pain in adults. It is a narcotic drug also called an opioid pain medication and available with the brand name of ultram, ultram Er, conzip. They are commonly used for treating long-term back pain and for relieving pain and discomfort from injuries. Tramadol works by binding to opioid receptors in the brain, effectively decreasing the feeling of pain. Tramadol capsules inhibit the reuptake of norepinephrine and serotonin in the reducing pain inhibitory pathways from the brain to spinal cord which activates pain inhibitory neurons in the spinal cord.
What is Celecoxib
Celecoxib is a type of NSAID medicine that is used to reduce pain and inflammation. It works by blocking the enzyme COX-2 in the body which produces the prostaglandins chemicals that are responsible for causing inflammation & pain and also for making skin warmer, inflamed when you get a fever. It is commonly used to treat mild to moderate pain including those related to osteoarthritis, rheumatoid arthritis, menstruation.
Functions Of Tramadol and Celecoxib
| Tramadol Functions | Celecoxib Functions |
| It is primarily used to treat moderate to severe pain. | It is used to treat pain relief and is anti-inflammatory that reduces pain and inflammation. |
| It acts on the central nervous system(CNS) and works by altering the way the brain perceives pain. | Blocks COX-2 enzyme responsible for inflammation and pain. |
| It is an opioid analgesic that binds to mu opioid receptors in the brain to reduce pain sensation. | It is used in arthritis treatment and also effective for osteoarthritis. |
| These medications inhibit regulation of norepinephrine and serotonin which enhances pain relief through neurotransmitters. | It helps in reducing swelling and joint pain. |
| It is used for both acute and chronic pain and also effective for post surgical pain, injury related pain and certain chronic conditions. | It has less digestion side effects compared to traditional NSAIDs, COX-1 helps in reducing stomach irritation. |
Dosage & Strengths Formation
What are the doses and strength of Tramadol
Tramadol Capsule is available in different strengths and forms such as 100mg, 200mg, and 30mg for extended release, and 50 mg for immediate release.
Lower dose starts from 25 mg per day, slowly you can increase your doses by 25 mg every 3 days as needed. You can take Tramadol 50mg to 100mg every 4 to 6 hours as needed. You can extend it to 400mg per day. These strengths are the immediate release tablets, capsules, and liquid.
You can take tramadol medication 100 mg once a day and by 100 mg every 5 days and if needed to a maximum dose of 300 mg per day.
What are the doses and strengths of Celecoxib
Celecoxib is available in capsule form and in several strengths including 50 mg, 100 mg, 200 mg, and 400 mg. The appropriate dose depends on the condition being treated. For osteoarthritis, the usual dose is 200 mg daily or you can take it as a single dose or divided into two. For rheumatoid arthritis 100mg to 200 mg twice daily may be used. As doses may be prescribed by a doctor, depending on an individual’s health condition and response.
How to take Tramadol & Celecoxib safely:
Before taking these medications you need to read all the instructions on how to take, when to take , when to stop, and what your dosages are. Here are the list of taking both capsules safely:
- You can take these capsules directly by mouth, with water or without water
- You need to know what your dosages are, take doses which are prescribed by your doctor to you.
- Do not crush, break and dissolve these medications , you can consume these directly by mouth without chewing.
- If you take these for a longer time and these don’t work on your body, concern your doctor as soon as possible.
- Do not take Tramadol & Celecoxib with any other medications.Take these medications alone or separately.
These all above are the safety advice so you can follow up with all the instructions or guidance before taking these pills. Share your past history related to health issues to your healthcare provider.
Side Effects Of Tramadol & Celecoxib
Adverse reactions or side effects of Tramadol
Sometime adverse reactions or side effects of tramadol may occur, these side effects decrease when you take it for a while. Here are the lists of Tramadol’s Side effects:
Common Side effects
- Dizziness
- Nausea
- Vomiting
- Drowsiness
- Headache
- Dry Mouth
Serious Side effects
- Depression
- Fast Heartbeat and sometime slow heartbeat Problem
Adverse reaction or side effects of Celecoxib
Common Side Effects
- Change in taste
- Stomach pain
- Gas
- Diarrhea
- Rashes and itching
Serious Side Effects
- Heart Attack
- Sweating
- Sudden severe headache
- Fast and slow heartbeating
- Weakness in the body
Precautions before taking Tramadol & Celecoxib
While taking these medications(Tramadol & Celecoxib) you need to follow the precautions and take guidance from a healthcare provider too. The list of precautions are given below:
- Do not take these medications if you are pregnant, and planning to be pregnant because it will be dangerous for a newborn and mother, may cause life threatening problems.
- Do not consume these medications with alcohol, it will be dangerous to your health.
- Take Tramadol & Celecoxib far away from children.
- Keep these drugs in the dark dry room, away from direct sunlight or heat.
- Do not take these medications if you are a heart patient or if you have a past history of any health related problem.