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Roxicodone (oxycodone) is a strong prescription pain medicine used to treat average to very bad pain. Roxicodone is a sedative pain medication sometimes called a narcotic. Which is available on our website where you can purchase it by using our online facility & can get the Best Quality Medicine at the cheapest price.

Roxicodone is used to treat severe pain enough to require opioid treatment. When other pain medicines do not work sufficiently or cannot handle the pain. It is owned by a group of medicines called narcotic analgesics (severe pain medicine). Oxycodone takes action on the central nervous system (CNS) to relieve pain.

What is Roxicodone prescribed for?

Roxicodone is a highly prescribed Oxycodone Hydrochloride Tablet that is used to relieve pain when other medicines do not work. Each variation of Roxicodone contains 15 to 20 mg of active Oxycodone Hydrochloride which is derived from opium alkaloid.

The inactive components of Roxicodone are Microcrystalline Cellulose, FD&C Blue No. 2 in 15 mg and 30 mg pills, Sodium Starch Glycolate, D&C Yellow No. 10 in 15 mg pills, Corn Starch, Stearic Acid, and Lactose. Along with that 15 mg tablets contain an equivalent of 13.5 mg oxycodone-free base and 30 mg pills contain 27.0 mg oxycodone-free base.

Roxicodone Prescription

For Adults: 10 to 30 milligrams (mg) every 4 hours as needed.

For Children: Take advice from a doctor or pharmacist.

Prescription of Roxicodone medicine is used to treat symptoms which moderate pain to severe pain and chronic severe pain. Roxicodone can be used alone or with other medicines. Roxicodone is the possession of a class of drugs called Opioid Analgesics.

How to use Roxicodone

Take the medicine through your mouth as directly as your doctor prescribed. This medicine you can easily take with food or without food through your mouth. If you have a sensation of vomiting, it will help to take this drug with food. Take guidance from your doctor, pharmacist, or medical care about different ways to decrease nausea (like lying down for 1 – 2 hours with a little head motion able to be done).

Also, keep in mind the below-mentioned points before starting the use of Roxicodone:

  • Don’t eat grapefruit or drink grapefruit juice while you are using this medication until or unless your doctor or pharmacist says you may do so safely. Grapefruit or Grapefruit juice can increase the chances of side effects with this medicine. Contact your doctor or medical care for more information.
  • If you are taking the liquid form of this medicine, measure the dose with a special measuring spoon/scoop. Do not use a household scoop. Take advice from your doctor about this. If you don’t know how to check or measure the dose.
  • Your dose is scheduled based on your medical condition/situation and response to treatment. Do not increase your dose without any advice from your doctor, take the medicine constantly, or take it for a longer time than prescribed.
  • If you take the medicine when the first indication of pain happens. it is most likely to show an effect. If you wait until the pain winds up, then the medication may not work.
  • If your pain is continuing (like due to cancer or other problems), In this case, this medicine is perhaps used for sudden pain only as needed.
  • If you are on other medicines, Tell your doctor about this before using Roxicodone so that the schedule can be adjusted for taking other medicines without any reaction.
  • If you suddenly stop this Oxycodone medicine, it may cause its side effects and chemical balance to be taken away, for the most part, if you have used it for a long time or in high doses. To prevent withdrawal, your doctor may lower your dose slowly. Withdrawal symptoms can vary from person to person but some of the most common symptoms are sweating, nausea, runny nose, muscle aches, trouble sleeping, watering eyes, anxiety, diarrhea, and sudden behavioral changes.

What to Know Before Taking Oxycodone?

Before starting your medication, read the Medical Guide to get a clear view of how the medication works. Also, discuss the points with your doctor/pharmacist if you find it difficult to understand them.

Before using this medication, tell about your medical history to your doctor or pharmacist if may you have taken any other medicine previously or previous year, especially if you have brain disorders (like head injury, tumor, seizures), or if you have breathing problems (like asthma, sleep apnea, chronic obstructive pulmonary disease-COPD), kidney disease, liver disease, mental/mood disorders.

Also, avoid eating high-fat meals before taking food. It is observed that the performance of the medicine is slowed down to 27% after such meals.

What are the benefits of using Roxicodone?

Roxicodone tablets are best to relieve moderate to sedative pain. Roxicodone extended-release tablets and extended-release capsules are the best for relieving severe pain in people who are facing high pain and need pain medicine around for a long time and who cannot be treated with other medicines. It is possible to order from our website & we will provide you with the best quality medicine that is FDA-approved.

Roxicodone extended-release tablets and extended-release capsules should not be used to prescribe medicine for pain that can be controlled by the medicine that it takes who needs it.

Roxicodone extended-release tablets, extended-release capsules, and concentrated solution should only be used to prescribe medicine for people who are forbearing (used to the effects of the medicine) to sedative medications because they have taken this type of medicine for at least one week (7 days).

Roxicodone is in a class of medications called an opiate (narcotic, sedative) painkiller drug. It works by changing the method of the brain and the nervous system to contract pain and interpret it.

Half-Life of Roxicodone:

Half-life in various variations of Roxicodone depends on the form of the medication and the way they are consumed. That is why there is a slight difference amongst the half-life of different mg’s of Roxicodone.

Roxicodone Doses Half-life(hours)
Roxicodone 5 mg Tablets 3.73
Roxicodone 15 mg Tablets 3.55
Roxicodone Liquid Form 15 mg Oral 3.71
Roxicodone 30 mg Tablets 3.85
Roxicodone 10 mg Oral Solution 2.9
Roxicodone 10 mg Oral Solution(Fed) 3.3

Side Effects of Roxicodone?

We will be providing Some side effects of Roxicodone to make it easy for you to classify and seek immediate help. Tell your doctor if there are any of these symptoms. Also, it is not the entire list of side effects. For a complete list, contact your doctor or paramedics.

  • Dry mouth ( xerostomia )
  • Vomiting
  • Itching(on the face, tongue, throat, etc.)
  • Stomach pain ( dyspepsia )
  • Drowsiness ( tiredness, fatigue )
  • Agitation
  • Confusion
  • Abdominal Pain(Stomach Pain)
  • Flushing ( dislodge )
  • Lightheadedness
  • Constipation
  • Hallucinations
  • Loss of Appetite
  • Undesired weight loss
  • Headache ( aggravation )
  • Mood changes ( explosiveness )
  • Breathing problems
  • Sleepness ( apnea )
  • A head injury or seizures
  • Drugs and alcohol addiction
  • Mental illness
  • Liver or kidney disease
  • Urination problems
  • Problems with your gallbladder, pancreas, or thyroid.

Effect of Roxicodone on the Central Nervous System

The CNS opioid receptors combine with Roxicodone to work all the way back from the spinal cord to the brain to generate analgesic effects for the drug. Roxicodone produces Respiratory(Central Nervous System) depression and depression of cough reflex of Medulla. This depression leads to a slight inactiveness of responsiveness of the Brain Stem and hence the brain feels less pain.

Effect of Roxicodone on the Gastrointestinal Tract

Roxicodone affects the entire Gastrointestinal Tract( Digestive Tract) differently. For example, it reduces mobility by decreasing the amount of Hydrochloric Acid in the stomach. It also delays the digestion of food and propulsive contractions. Roxicodone also stimulates the Chemoreceptor Trigger Zone of the medulla leading to nausea and feeling of vomitting. Some other effects of Roxicode on the Gastrointestinal Tract are a reduction in pancreatic secretions, spasms, biliary, and elevations in serum amylase.

Effect of Roxicodone on the Cardiovascular System:

Roxicodone increases Peripheral Vasodilatation and affects Baroreceptor Reflexes in the Cardiovascular System leading to side effects such as pruritus, orthostatic hypotension, sweating, flushing, red eyes, hypotension, and such.

Warning and Precautions of Taking Roxicodone


One of the greatest hazards of Roxicodone is Respiratory Depression which generally happens in the older population. Roxicodone causes serious breathing problems during the first 24 to 72 hours of your medical care and any time your dose is increased. Your doctor will observe you carefully during your health treatment. Contact your doctor when you have faced slowed breathing or asthma or other related problems.

While on the medication, a patient becomes vulnerable to other breathing issues such as a decrease in respiratory reserve, hypercapnia, hypoxia, and other breathing issues. Hence it is advised to be extremely cautious while taking Roxicodone if you have breathing problems.

If you take other medicines with Roxicodone it may increase the chance risk of life-terrifying/scary breathing problems, sedation, or coma. Take advice from your doctor and pharmacist if you are taking the medicine or plan to take this medicine or any of the following medicines: certain antibiotics like clarithromycin (Biaxin, in PrevPac) and erythromycin (Ery Tab, Erythrocin).

Your doctor will observe you carefully and if you need to change the dose of your Roxicodone medicine do not change without a doctor’s guidance. When you take Roxicodone with any other type of medicine and you develop any of the following symptoms, contact your doctor right away or look up emergency medical care: extreme sleepiness, unusual dizziness, difficulty breathing. Make sure that your family members know these symptoms as these may be serious so they can call the doctor or emergency help in an emergency situation.


During pregnancy in women, Take this medicine when only you need it because it may harm the unborn baby. The side effects of Roxicodone Poisoning can also be observed in the baby if the mother misuses them. These side effects are poor feeding habits, continuous crying for hours, shaking, and either extreme low weight or extreme high weight.

Drugs are passed into breast milk then it may be harmful or may have unsatisfactory effects on a breastfeeding baby. Take advice from your doctor immediately and if your baby develops unusual sleepiness, difficulty feeding, or face trouble breathing, immediately stop feeding him the milk. Take advice from your doctor before breastfeeding. It’s good for both.

Be extremely careful while using Roxicodone under the following conditions:

  • CNS depression
  • Acute Alcoholism
  • Convulsive Disorders
  • Urethral Stricture
  • Delirium Tremens
  • Myxedema
  • Kyphoscoliosis
  • Hepatic Impairment
  • Toxic Psychosis
  • Renal Function
  • Addison’s disease
  • Brain Tumor
  • Paralytic Ileus
  • Pancreatitis


The best way to store and preserve Roxicodone is to store it at room temperature(without moisture). Keep it away from direct sunlight and below 77°F. Do not change the original packaging of the medication.

For more storage information, read the instructions given at the back of the medicine pack.

Drug Interaction of Roxicodone

Drug interactions will change how your medicines work and drug interactions can increase your risk for serious side effects. Do not start any other medicine with this medicine and also do not take your regular medicines without taking a doctor’s advice. This medicine can interfere with laboratory tests, possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drugome product that interacts with this drug including pain medications naltrexone, and samidorphan.

The medicines/drugs/herbs that react with Roxicodone are mentioned below. These are not the entire list of reactive medicines. For the entire list, contact your pharmacist.

  • Butorphanol
  • Pentazocine
  • Ketoconazole
  • Codeine
  • Alprazolam
  • Zolpidem
  • Rifampin
  • Carbamazepine,
  • Phenytoin
  • Cetirizine
  • Cough and cold syrups
  • Nalbuphine
  • Hydrocodone
  • Cannabis
  • Rifabutin
  • Ritonavir
  • Lorazepam
  • Carisoprodol
  • Cyclobenzaprine
  • Diphenhydramine
  • Mifepristone,
  • Tipranavir


If some take overdoses and need help with serious symptoms such as passing out or a problem breathing, give them Naloxone if available. If the person is awake and with no symptoms, call a poison control centre right away at 1-800-222-1222. These are Symptoms of overdose: facing problems during breathing, bradycardia, skeletal muscle flaccidity, stupor, clammy skin, constricted pupils, hypotension, slow heartbeat, and coma.

Roxicodone medicine is specially ordered for your current condition only. Don’t use it later in another situation unless said by your doctor. In such a case, alternate medications may be needed.

If naloxone is not available to treat opioid overdose then talk with your doctor or pharmacist. Tell the lessons to your family members about the indications of a sedative overdose. Make sure you take one dose of this medicine at a single time

Elimination of Roxicodone

All the active and inactive ingredients of Roxicodone are processed by kidneys and excreted in the form of urine. The urinal waste contains 19% free Roxicodone, 50% Conjugated Roxicodone, 0.8 L/min Plasma Clearance, and some traces of conjugated Noroxycodone.

Frequently Asked Questions

Q. How much Roxicodone is absorbed in the blood?

Different variations of Roxicodone take different time to get absorbed. Roxicodone 15 mg gets 96% absorbed with respect to 5 mg and Roxicodone 30 mg gets 101% absorbed with respect to 5 mg. It takes approximately 24 hours at max. for the pills to completely dissolve.

Q. Is Roxicodone the same as Percocet?

Roxicodone is sold under the brand name of Oxycodone and some other different brand names too and also contains derivatives of morphine and it includes OxyContin. Percocet is a mixture of oxycodone and acetaminophen.

Q. How long does it take for Roxicodone to work?

Roxicodone medicine (capsules and liquid) takes around 30 to 60 minutes to work. But these wear off after 4 to 6 hours. Roxicodone (tablets) can take 1 to 2 days to work completely, but the pain relief is long-established.

Q. Does Roxicodone make you sleepy?

The side effect (sleepiness) completely depends from person to person. If a patient’s body can easily metabolize the drugs, then it does not feel sleepy.