Symbalta is also known as duloxetine and Tramadol are two well known medications for managing chronic pain conditions. Although both are used for similar cases but they can’t be prescribed for the same condition. Because they also carry some significant differences, so users need to know about the Cymbalta Vs Tramadol differences in detail. Because choosing the right medication is very important due to their different benefits and risks. In this article we’ll discuss about how they work together, and what are the associated adverse effects. It is important to help the patient as well as the physician for making an informed decision to take the pill. 

What Is Cymbalta And How It Work?

Cymbalta is a brand name for Duloxetine hydrochloride, which is available in only prescription comes under SNRI(serotonin-norepinephrine reuptake inhibitor). It is clinically approved for major depressive disorder (MDD), generalised anxiety disorder, diabetic nerve pain (neuropathy), or chronic musculoskeletal pain. Cymbalta works by increasing Serotonin and Norepinephrine in the brain to relieve pain. It doesn’t work by blocking the pain signals like opioids, it changes how the brain processes the pain. By increasing these two neuron chemicals it regulates the mood and reduces pain significantly. 

What Is Tramadol And How It Work?

Tramadol is an opioid pain reliever and also has SNRI-like effects. It is generally prescribed when other acetaminophen or NSAIDs aren’t enough. It works by binding mu-opioid receptors in the brain and increases pain tolerance. That results relieving pain gradually in few times. Tramadol pill is generally considered as weaker opioid, that is used in minor pain relief cases. Therefore, it is generally prescribed for minor pain conditions where higher-dose opioids can be skipped. 

Which Is Better, Cymbalta Or Tramadol?

From the above lines you have known that Cymbalta and Tramadol works in different ways and don’t fit in similar conditions. So, it is important to know, which is better from them to achieve better outcomes. Selecting the appropriate pill is also important to avoid any negative interactions. Whether you’re suffering from chronic pain or depression, knowing the benefits as well as risks will help you choosing both or one of them. For some identical properties people are confused about Is Tramadol similar to Cymbalta? To know this, let’s explore their properties in below.

Similarities in Cymbalta and Tramadol

Although both are composed of different chemicals and works in different way they have some similar properties. For this they can be used together under medical supervision. 

• Cymbalta and Tramadol affects Serotonin and Norepinephrine in the brain to relieve pain. 
• These two pills are not considered as first-line treatment, it is prescribed when other doses are not worked well. 
• Both pills are prescribed for similar type of pain conditions like Fibromyalgia, Chronic musculoskeletal pain, or Neuropathic pain. 
• Both the pills can interact with CNS medications like sedatives, antidepressants, and anti-anxiety medications. 
• Similar type of side effects can cause these two pills like withdrawal symptoms, serotonin syndrome, and mental illness. So both the pill needs to be taken under the supervision of a physician. 

Tramadol Vs Cymbalta: Key Differences Between Two Pain Killers

Cymbalta and Tramadol designed differently to serve different cases. But sometimes their resources matches with each other, for which knowing their contrasts is the most important factor to avoid risk profiles. 

• Primary use of Tramadol and Cymbalta is quite different from eachother according to the severity of pain. Tramadol cures only pain but Cymbalta cures nerve issues as well as associated pain. 
• Both Tramadol and Cymbalta affects serotonin and norepinephrine. Here, the difference is Tramadol inhibits them and Cymbalta balance them. 
• Tramadol has higher addictive potential than the Cymbalta, so longer use of Tramadol is is not suggested anymore. 
• In rare cases both pill can cause side effects. Where Tramadol causes sedation, on other hand, Cymbalta causes insomnia(sleeplessness) to he patient. 

Duloxetine And Tramadol Interaction

If you have been prescribed or suffers from pain due to nerves problem, must know their interaction. Most of us are confused about, “can i take duloxetine and tramadol together?” So let’s know what will be happened when we combine them together. 

Combining Tramadol and Cymbalta will give enhanced pain relief on nerve pain and physical pain. Cymbalta and tramadol for fibromyalgia has been a magical solution used by most people. This combo also helps to reduce need of higher opioid doses. For serious diseases like Osteoarthritis, Diabetic neuropathy, or Chronic low-back pain this combo relief the patients at lower doses, when other single methods are not worked well. This combination medication boosts mood as well as relieves pain combinely. 

Despite of above benefits, the combined form can cause harmful effects if they are not managed carefully. It can cause major risks like serotonin syndrome, including anxiety, fever, sweating, muscle stiffness, diarrhea, rapid heart rate & high blood pressure. Possibility of seizures is increases when you take the higher dose of both. 

Conclusion

From the above discussion, we can conclude that both are safe medications for use. But to clear about should these medications be taken together or not some factors must be carried out. The medications must be taken under the guidance of a physician, and the amount of dose must be as per the prescription. While the combination helps relieve certain conditions, they must be taken with prescribed manner. Otherwise, strong adverse effects might feels uneasy to you.