Can Oxycodone Cause Dehydration?
Short answer: Oxycodone is not a diuretic and does not directly “dry you out,” but it can lead to dehydration indirectly. Nausea and vomiting, sedation that reduces how much you drink, sweating, constipation-related eating changes, and withdrawal-related diarrhea can all leave you short on fluid. Dehydration matters more with oxycodone because it can raise dizziness …