Oxycodone and Magnesium

Short answer: There is no well-documented, clinically significant drug interaction between oxycodone and ordinary magnesium supplements in healthy adults. Many people take both, and magnesium is often used to ease the constipation oxycodone causes. The real cautions are narrower than most people expect: kidney problems, very high magnesium intake, laxative overuse, and the timing of …

Can Oxycodone Cause Acid Reflux?

Yes, oxycodone can cause acid reflux. It doesn’t make your stomach produce more acid. Instead, it slows the movement of food out of the stomach and changes how the food pipe (esophagus) contracts, giving acid more opportunity to travel upwards. For some people this means occasional heartburn after meals. For others, especially those who already …